Yeah, they’re partly genetic but you can risk it. I have a couple of friends who have had their third or fourth stone and I’ve never felt so much as a slight discomfort on my kidneys. It makes me wonder wtf they’re doing to themselves but I’m not one to judge.
Ibuprofen is mostly processed by your liver as well. Acetaminophen uses a bit of both.
This appears to occur predominantly systemically in the liver [1,10], but may occur pre-systemically in the gut as well [11]. Ibuprofen is almost completely metabolized, with little to no unchanged drug found in the urine [1,9,12].
Tylenol (acetaminophen) is almost completely broken down by the liver. During this process, a toxic chemical forms. Normally, the liver makes it non-toxic. But if you take too much Tylenol, the liver can’t properly process it all. The toxic chemical can then build up and poison liver cells.
That was definitely the cause of my kidney stone, because I don’t take OTC pain meds frequently, but if you do have ways to avoid kidney stones, avoid kidney stones. They are no fun.
My friend works out and takes pain meds frequently.
He also complains about yearly kidney stones.
I have never had a kidney stone. Where he’s on his 8th one.
Yeah, they’re partly genetic but you can risk it. I have a couple of friends who have had their third or fourth stone and I’ve never felt so much as a slight discomfort on my kidneys. It makes me wonder wtf they’re doing to themselves but I’m not one to judge.
Was he on narcotics? I’m finding no link between Acetaminophen or Ibuprofen to kidney stones. Just drink more water.
https://www.utsouthwestern.edu/newsroom/articles/year-2023/june-prevent-kidney-stones.html
https://pubmed.ncbi.nlm.nih.gov/30829133/
Ibuprofen is mostly processed by your liver as well. Acetaminophen uses a bit of both.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355401/
https://www.goodrx.com/acetaminophen/is-tylenol-acetaminophen-bad-for-your-liver-or-kidneys
https://pubmed.ncbi.nlm.nih.gov/8669426/
https://www.goodrx.com/acetaminophen/is-tylenol-acetaminophen-bad-for-your-liver-or-kidneys
That was definitely the cause of my kidney stone, because I don’t take OTC pain meds frequently, but if you do have ways to avoid kidney stones, avoid kidney stones. They are no fun.